Laboratory of Neuroontogenesis
Brief history of the laboratory
The laboratory of neuroontogenesis was formed in 1989 and belongs to the scientific school of academician Peter Kuzmich Anokhin. The laboratory develops ideas about system genesis, developmental heterochronies and functional systems. Her origins are Kira Vasilyevna Shuleykina and Sergey Naumovich Khayutin. Laboratory research aims to solve the following problems: · the role of environmental factors (afferent influx) in the formation of the structure and functions of the developing brain. · The study of the role of early sensory experience in the formation of memory and learning of adult animals. · The study of the structural and functional bases of the formation of early forms of behavior and the modification of their sensory support in the subsequent stages of postnatal ontogenesis. · Study of integrative interactions in the nervous system during normal ontogenesis, under conditions of restriction of sensory input and with genetically determined developmental disorders.
Список сотрудников
Publication list
Papers
- Sitnikova E.Y., Hramov A.E., Koronovsky A.A., VanLuijtelaar G. Sleep spindles and spike-wave discharges in EEG: Their generic features, similarities and distinctions disclosed with Fourier transform and continuous wavelet analysis. Journal of Neuroscience Methods. 2009. V. 180. N. 2. P. 304-316. DOI: 10.1016/j.jneumeth.2009.04.006
- Sitnikova E.Y., VanLuijtelaar G. Electroencephalographic precursors of spike-wave discharges in a genetic rat model of absence epilepsy: Power spectrum and coherence EEG analyses. Epilepsy Research. 2009. V. 84. N. 2-3. P. 159-171. DOI: 10.1016/j.eplepsyres.2009.01.016
- Sysoeva O.V., Maluchenko N.V., Smirnov K.S., Shleptsova V.A., Ivanitsky A.M., Tonevitsky A.G. Peculiarities of brain information processing in persons with different serotonin transporter gene variants. Bulletin of Experimental Biology and Medicine. 2009. V. 148. N. 5. P. 731-734. DOI: 10.1007/s10517-010-0803-9
- Budilin S.Y., Pasikova N.V., Midzyanovskaya I.S., Ioffe M.E. Effect of apomorphine injection into the nucleus accumbens on the limb preference in manipulation movements in rats. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2008. V. 58. N. 3. P. 339-344.
- Budilin S.Y., Midzyanovskaya I.S., Shchegolevskii N.V., Ioffe M.E., Bazyan A.S. Asymmetry in dopamine levels in the nucleus accumbens and motor preference in rats. Neuroscience and Behavioral Physiology. 2008. V. 38. N. 9. P. 991-994. DOI: 10.1007/s11055-008-9082-6
- Sitnikova E.Y., Dikanev T., Smirnov D., Bezruchko B., VanLuijtelaar G. Granger causality: Cortico-thalamic interdependencies during absence seizures in WAG/Rij rats. Journal of Neuroscience Methods. 2008. V. 170. N. 2. P. 245-254. DOI: 10.1016/j.jneumeth.2008.01.017
- Korneeva E.V., Golubeva T.E., Alexandrov A.V., Gurjeva T.I., Dadasheva O.A., Sychev V.N., Raevsky V.V. Prenatal acoustic stimulation and feeding behavior of Japanese quail chicks (Coturnix coturnix japonica). Aviakosmicheskaja i Ekologicheskaja Meditsyna. 2007. V. 41. N. 1. P. 47-50.
- Korneeva E.V., Golubeva T.E., Alexandrov L.I., Gurieva N.S., Dadasheva O.A., Sychev V.N., Raevsky V.V. Prenatal acoustic stimulation and feeding behavior of Japanese quail chicks (Coturnix coturnix japonica). Aviakosmicheskaya i Ecologicheskaya meditsina. 2007. V. 41. N. 1. P. 47-50.
- Koronovsky A.A., Minukhin I.M., Tyshenko A.A., Khramov A.E., Midzyanovskaya I.S., Sitnikova E.Y., VanLuijtelaar G.., VanRijn C.M. Using continuous wavelet transform to analyze intermittent behavior. Prikladnaja i nelinejnaja dinamika. 2007. V. 15. N. 4. P. 34-54.
- Sargsyan A., Sitnikova E.Y., Melkonyan A., Mkrtchian H., VanLuijtelaar G. Simulation of sleep spindles and spike and wave discharges using a novel method for the calculation of field potentials in rats. Journal of Neuroscience Methods. 2007. V. 164. N. 1. P. 161-176. DOI: 10.1016/j.jneumeth.2007.03.023
- Sitnikova E.Y., VanLuijtelaar G. Electroencephalographic characterization of spike-wave discharges in cortex and thalamus in WAG/Rij rats. Epilepsia. 2007. V. 48. N. 12. P. 2296-2311. DOI: 10.1111/j.1528-1167.2007.01250.x
- Korneeva E.V., Alexandrov L.I., Golubeva T.B., Raevsky V.V. Development of hearing sensitivity and formation of acoustically driven defensive behavior of Ficedula hypoleuca. Zhurnal Evolutsionnoi Biokhimii i Fiziologii. 2006. V. 42. N. 6. P. 548-553.
- Koronovsky A.A., Kuznetsova G.D., Midzyanovskaya I.S., Sitnikova E.Y., Trubetskov D.I., Khramov A.E. Patterns of intermittent behavior in spontaneous non-convulsive convulsive activity in rats. Doklady Akademii Nauk. 2006. V. 409. N. 2. P. 274-276.
- Kudryashova I.E., Pigareva M.L., Kudryashova I.V. Prenatal experience and postnatal development in rat's hippocampus: consequences of sleep deprivation. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2006. V. 56. N. 3. P. 401-407.
- Hramov A., Koronovskii A.A., Midzyanovskaya I.S., Sitnikova E.Y., VanRijn C.M. On-off intermittency in time series of spontaneous paroxysmal activity in rats with genetic absence epilepsy. Chaos. 2006. V. 16. N. 4. P. 043111. DOI: 10.1063/1.2360505
- Sitnikova E.Y., VanLuijtelaar G. Cortical and thalamic coherence during spike-wave seizures in WAG/Rij rats. Epilepsy Research. 2006. V. 71. N. 2-3. P. 159-180. DOI: 10.1016/j.eplepsyres.2006.06.008
- VanLuijtelaar G., Sitnikova E.Y. Global and focal aspects of absence epilepsy: The contribution of genetic models. Neuroscience and Biobehavioral Reviews. 2006. V. 30. N. 7. P. 983-1003. DOI: 10.1016/j.neubiorev.2006.03.002
- Korneeva E.V., Alexandrov L.I., Golubeva T.B., Raevsky V.V. The role of visual afferentation in the development of early defense behavior of pied flycatcher nestlings. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2005. V. 55. N. 3. P. 353-359.
- Sitnikova E.Y., Raevsky V.V. Morphological basis for compensating sensory deficit in early ontogenesis. Novosti Mediko-Biologicheskikh Nauk. 2005. V. 2. P. 5-11.
- Biryukova L.M., Midzyanovskaya I.S., Lensu S., Tuomisto L. Distribution of D<inf>1</inf>-like and D<inf>2</inf>-like dopamine receptors in the brain of genetic epileptic WAG/Rij rats. Epilepsy Research. 2005. V. 63. N. 2-3. P. 89-96. DOI: 10.1016/j.eplepsyres.2004.12.001
- Sitnikova E.Y., Luijtelaar G.V. Reduction of adrenergic neurotransmission with clonidine aggravates spike-wave seizures and alters activity in the cortex and the thalamus in WAG/Rij rats. Brain Research Bulletin. 2005. V. 64. N. 6. P. 533-540. DOI: 10.1016/j.brainresbull.2004.11.004
- Midzyanovskaya I.S., Kuznetsova G.D., Vinogradova L.V., Shatskova A.B., Coenen A.M., VanLuijtelaar G. Mixed forms of epilepsy in a subpopulation of WAG/Rij rats. Epilepsy and Behavior. 2004. V. 5. N. 5. P. 655-661. DOI: 10.1016/j.yebeh.2004.06.021
- Sitnikova E.Y., VanLuijtelaar G. Cortical control of generalized absence seizures: Effect of lidocaine applied to the somatosensory cortex in WAG/Rij rats. Brain Research. 2004. V. 1012. N. 1-2. P. 127-137. DOI: 10.1016/j.brainres.2004.03.041
- Raevsky V.V., Dawe G.S., Stevenson J.D. Endogenous dopamine modulates corticopallidal influences via GABA. Neuroscience and behavioral physiology. 2003. V. 33. N. 8. P. 839-844. DOI: 10.1023/A:1025113818854
- Sarkisova K.Y., Midzyanovskaya I.S., Kulikov M.A. Depression-like behavioral alterations and c-fos expression in the dopaminergic brain regions in WAG/Rij rats with genetic absence epilepsy. Behavior and Brain Research. 2003. V. 144. N. 1-2. P. 211-226. DOI: 10.1016/S0166-4328(03)00090
- Raevsky V.V. Reorganization of functional systems in ontogenesis. Zhurnal Evolutsionnoy Biokhimii i Fiziologii. 2002. V. 38. N. 5. P. 502-506.
- Sarkisova K.Y., Midzyanovskaya I.S., Kulikov M.A. Depression-like change in behaviour and expression of c-fos gene in dopaminergic brain structures in Wag/Rij rats. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2002. V. 52. N. 6. P. 733-742.
- Raevsky V.V., Dawe G.S., Stevenson J.D. Endogenous dopamine modulates cortico-pallidal influence via GABA. Rossijskij Fiziologicheskij Zhurnal im I M Sechenova. 2002. V. 88. N. 6. P. 723-730.
- Sitnikova E.Y. Vibrissectomy during early ontogenesis in rats disturbs the functional properties of cortical projection neurons. Neuroscience and Behavioral Physiology. 2001. V. 31. N. 2. P. 153-156. DOI: 10.1023/A:1005204005811
- Raevsky V.V. Does a concept of the higher nervous activity correspond to the modern state of the behavioral science?. Rossijsjij Fiziologicheskij Zhurnal im I M Sechenova. 2000. V. 86. N. 2. P. 235-237.
- Sitnikova E.Y. Vibrissectomy in rats in early ontogenesis disrupts the functional properties of projection cortical neurons. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2000. V. 50. N. 8. P. 138-142.
- Sitnikova E.Y. The effects of restricting afferent input during early ontogenesis on evoked activity of projection neurons depend on the maturity of the sensory inputs. Neuroscience and Behavioral Physiology. 2000. V. 30. N. 6. P. 645-648. DOI: 10.1023/A:1026642615161
- Kudryashova I.E., Kudryashova I.V., Sitnikova E.Y., Raevsky V.V. The effect of forelimb deafferentation in early postnatal ontogeny on the development of synaptic transmission in the hippocampus. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 1999. V. 49. N. 4. P. 554-565.
- Kudryashov I.E., Kudryashova I.V., Sitnikova E.Y., Raevsky V.V. The influence of deafferentation of the forelimb in early postnatal ontogenesis on the formation of synaptic transmission in the hippocampus. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 1999. V. 49. N. 4. P. 629-634.
- Sitnikova E.Y. The influence of limitation of sensory influx in early ontogenesis on the induced activity of projection neurons depends on the degree of maturity of sensory inputs. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 1999. V. 49. N. 3. P. 505-510.
- Sitnikova E.Y. Partial forelimb deafferentation during early ontogenesis in rats increases somatosensory cortex neuron reactivity. Neuroscience and Behavioral Physiology. 1999. V. 29. N. 2. P. 181-183. DOI: 10.1007/BF02465324
- Kudryashov I.E., Kudryashova I.V., Raevsky V.V. Ribonuclease improves the state of hippocampal sections in the post-ischemic period. Neuroscience and Behavioral Physiology. 1998. V. 28. N. 4. P. 357-365. DOI: 10.1007/BF02464788
- Kudryashov I.E., Kudryashova I.V., Raevsky V.V. Ribonuclease improves the function of hippocampal slices in the postischemic period. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 1997. V. 47. N. 1. P. 136-146.
- Raevsky V.V., Alexandrov L.I., Vorobieva A.D., Korneeva E.V., Kudryashov I.E., Kudryashova I.V., Pigareva M.L., Sitnikova E.Y., Stashkevich I.S. Sensory information is an important factor in ontogenesis. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 1997. V. 47. N. 2. P. 299-307.
- Sitnikova E.Y. Partial deafferentation of the forelimbs in rats in early ontogenesis increases the reactivity of neurons in the somatosensory cortex. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 1997. V. 47. N. 6. P. 1051-1054.
- Raevsky V.V., Alexandrov L.I., Vorobyeva A.D., Golubeva T.B., Korneeva E.V., Kudriashov I.E., Kudriashova I.V., Pigareva M.L., Sitnikova E.Y., Stashkevitch I.S. Sensory information - The major factor of ontogeny. Neuroscience and Behavioral Physiology. 1997. V. 27. N. 4. P. 455-461. DOI: 10.1007/BF02462947
- Raevsky V.V. The physiology of higher nervous activity. Uspekhi Fiziologicheskikh Nauk. 1994. V. 25. N. 2. P. 23-27.
- Raevsky V.V., Tegetmayer C., Trifonov A.A. Does the destruction of catecholaminergic neurons in newborn rats influence the modulator function of the cholinergic system?. Neuroscience and Behavioral Physiology. 1993. V. 23. N. 6. P. 529-533. DOI: 10.1007/BF01153679
- Raevsky V.V., Tegetmeier H., Budko K.P. Destruction of the catecholaminergic system in newborn rats impedes the formation of cholinergic innervation of the neocortex. Neuroscience and Behavioral Physiology. 1993. V. 23. N. 4. P. 333-335. DOI: 10.1007/BF01183025
- Raevsky V.V., Tegetmayer S.., Trifonov A.A. Does the destruction of the catecholaminergic neurons in newborn rat pups influence the modulatory function of the cholinergic system?. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 1992. V. 42. N. 5. P. 1018-1022.
- Raevsky V.V., Tegetmeyer K.A., Budko K.P. The destruction of the catecholaminergic system in newborn rats hinders the formation of cholinergic innervation of the neocortex. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 1992. V. 42. N. 2. P. 396-399.
- Teleuova T.S., Mustafina Z.G., Raevsky V.V. Laser therapy in the treatment of complications of radiotherapy of the eyelids in children. Vestnik Oftalmologii. 1992. V. 108. N. 1. P. 21.
- Pigareva M.L., Preobrazhenskaya L.A. Comparative psychological approach to the analysis of the functions of the hippocampus. Neuroscience and Behavioral Physiology. 1991. V. 21. N. 3. P. 238-246. DOI: 10.1007/BF01191661
- Pigareva M.L. Homogeneous (food) conditioned reflex switching in rats after simultaneous injury to the hippocampus and amygdala. Neuroscience and Behavioral Physiology. 1983. V. 13. N. 1. P. 34-40. DOI: 10.1007/BF01189621