Laboratory of Human Higher Nervous Activity

The main areas of research

Neurophysiological basis of human cognitive functions in healthy and pathological brain

Perception

Attention

Emotions

Memory

Thinking

Consciousness (levels, content, form)

Basic research methods

Evoked potentials

EEG

Vegetative indices

fMRI (behavior and resting state)

Psychometric tests

History

The laboratory of higher nervous activity of a person was organized at the Institute in 1987. Its task was defined as studying the physiological foundations of consciousness. From 1987 to 2012, the laboratory was headed by prof. A.M. Ivanitsky, who had developed the theory of information synthesis shortly before. The theory was based on a study of the physiological processes underlying sensations. Following this theory, psychic (subjectively experienced) phenomena arise as a result of the return of excitation to areas of initial projections, comparison, and synthesis in the cortex of new information with previous extracted from memory and comes from centers of motivation.

Список сотрудников

Publication list

Papers

Miasnikova A., Perevoznyuk G., Martynova O.V., Baklushev M. Cross-frequency phase coupling of brain oscillations and relevance attribution as saliency detection in abstract reasoning. Neuroscience Research. 2020. DOI: 10.1016/j.neures.2020.05.012
Portnova G., Girzhova I., Filatova D., Podlepich V., Tetereva A., Martynova O. Brain Oscillatory Activity during Tactile Stimulation Correlates with Cortical Thickness of Intact Areas and Predicts Outcome in Post-Traumatic Comatose Patients. Brain Sciences. 2020. V. 10. N. 10. P. 720. DOI: 10.3390/brainsci10100720
Portnova G.V., Tetereva A., Ivanitsky A.M., Martynova O.V., Liaukovich K.M. The effect of experimental conditions, the sample size and session duration on resting-state subjective experience. Psychology, Journal of the Higher School of Economics. 2020. V. 17. N. 3. P. 592-607. DOI: 10.17323/1813-8918-2020-3-592-607
Sharova E.V., Kotovich Ju.V., Deza-Araujo Y.I., Smirnov K.S., Gavron A.A., Fadeeva L.M., Chelyapina-Postnikova M.V., Alexandrova E.V., Vronkova L.A., Boldyreva G.N., Verkhlyutov V.M., Kornienko V.N., Pronin I.N. fMRI resting state networks visualization in patients with severe traumatic brain injury. Medical Visualization. 2020. V. 24. N. 1. P. 68-84. DOI: 10.24835/1607-0763-2020-1-68-84
Stroganova T.A., Komarov K.S., Sysoeva O.V., Goiaeva D.E., Obukhova T.S., Ovsiannikova T.M., Prokofyev A.O., Orekhova E.V. Left hemispheric deficit in the sustained neuromagnetic response to periodic click trains in children with ASD. Molecular Autism. 2020. V. 11. N. 1. P. 100. DOI: 10.1186/s13229-020-00408-4
Sysoeva O.V., Molholm S., Djukic A., Frey H.P., Foxe J.J. Atypical processing of tones and phonemes in Rett Syndrome as biomarkers of disease progression. Transl Psychiatry. 2020. V. 10. N. 1. P. 188. DOI: 10.1038/s41398-020-00877-4
Tetereva A., Kartashov S., Ivanitsky A.M., Martynova O.V. Variance and Scale-Free Properties of Resting-State Blood Oxygenation Level-Dependent Signal After Fear Memory Acquisition and Extinction. Frontiers in Human Neuroscience. 2020. 14:509075.. DOI: 10.3389/fnhum.2020.509075
Tetereva A.O., Balaev V.V., Kartashov S.I., Ushakov V.L., Ivanitsky A.M., Martynova O.V. Asymmetry of amygdala resting-state functional connectivity in healthy human brain. Neuroreport. 2020. V. 31. N. 1. P. 17-21. DOI: 10.1097/WNR.0000000000001353
Ukraintseva Y.V. Selective slow-wave sleep suppression affects glucose tolerance and melatonin secretion. The role of sleep architecture. Sleep Medicine. 2020. DOI: 10.1016/j.sleep.2019.11.1254
Garakh Z.V., Rebreikina A.B., Strelets V.B., Golikova A.V., Zaytseva Y. Neural mechanisms of reading. Zh. Vyssh. Nerv. Deiat. I. P. Pavlova. 2019. V. 69. N. 3. 294 - 313. DOI: 10.1134/S0044467719030055
Brima T., Molholm S., Molloy C.J., Sysoeva O.V., Nicholas E., Djukic A., Freedman E.G., Foxe J.J. Auditory sensory memory span for duration is severely curtailed in females with Rett syndrome. Translational Psychiatry. 2019. V. 9. N. 1. P. 130. DOI: 10.1038/s41398-019-0463-0
Chemerisova E.V., Martynova O.V. Effects of the Phonological Loop of Working Memory on the Productivity of Solving Mathematical and Verbal Tasks in Specialists in Mathematics and the Humanities. Neuroscience and Behavioral Physiology. 2019. V. 49. N. 7. P. 857-862. DOI: 10.1007/s11055-019-00812-1
Portnova G.V., Ukraintseva Y.V., Liaukovich K.M., Martynova O.V. Association of the retrospective self-report ratings with the dynamics of EEG. Heliyon. 2019. V. 5. N. 10. e02533. DOI: 10.1016/j.heliyon.2019.e02533
Sysoeva O.V., Smirnov K., Stroganova T.A. Sensory evoked potentials in patients with Rett syndrome through the lens of animal studies: Systematic review. Clinical Neurophysiology. 2019. V. 131. N. 1. P. 213-224. DOI: 10.1016/j.clinph.2019.11.003
Ukraintseva Y.V., Liaukovich K.M., Sake K.L., Polishchuk A.A., Martynova O.V. Improvements in the Recognition of Sounds after Presentation during Sleep. Neuroscience and Behavioral Physiology. 2019. V. 49. N. 9. P. 1159-1168. DOI: 10.1007/s11055-019-00853-6
Verkhlyutov V.M., Balaev V.V., Ushakov V.L., Velichkovsky B.M. A novel methodology for simulation of EEG traveling waves on the folding surface of the human cerebral cortex. Studies in Computational Intelligence. 2019. V. 799. P. 51-63. DOI: 10.1007/978-3-030-01328-8_4
Arkhypov A.Y., Novototsky-Vlasov V.Y., Nurbekov M.K., Strelets V.B. The influence of negative emotional stimuli on the late perception stages (P300 & N400 components) in patients with paranoid schizophrenia in implicite situation. Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova. 2018. V. 68. N. 1. P. 28-40. DOI: 10.7868/S0044467718010033
Kovrov G.V., Merkulova T.B., Posokhov S.I., Garakh Z.V. The dynamics of the peak frequency of the alpha rhythm when falling asleep. Buleten Eksperimentalnij Biologii i Meditsiny. 2018. V. 165. N. 2. P. 136-139.
Ukraintseva Y.V., Levkovich K.M., Sake K.L., Polishchuk A.A., Martynova O.V. Improvement of acoustical discrimination after sound presentation during sleep. Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova. 2018. V. 68. N. 5. P. 614-626. DOI: 10.1134/S004446771805012X
Chemerisova E.V., Atanov M.S., Mikheev I.N., Martynova O.V. Classification of verbal and mathematical mental operations based on the power spectral density of EEG. Psychology, Journal of the Higher School of Economics. 2018. V. 15. N. 2. P. 268-278. DOI: 10.17323/1813-8918-2018-2-268-278
Chemerisova E.V., Martynova O.V. Phonological loop of working memory affects performance in solving mathematical and verbal tasks in specialists of mathematics and humanities. Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova. 2018. V. 68. N. 3. P. 340-348. DOI: 10.7868/S0044467718030073
Balaev V., Orlov I., Petrushevsky A., Martynova O.V. Functional connectivity between salience, default mode and frontoparietal networks in post-stroke depression. Journal of Affective Disorders. 2018. V. 227. P. 554-562. DOI: 10.1016/j.jad.2017.11.044
Garakh Z.V., Zaitseva Y.S., Novototskii-Vlasov V.Y., Gurovich I.Y., Shmukler A.B., Strelets V.B. Effects of Instructions on the Early Stages of the Visual Perception of Verbal Stimuli in Health and Schizophrenia. Neuroscience and Behavioral Physiology. 2018. V. 48. N. 4. P. 463-473. DOI: 10.1007/s11055-018-0587-3
Knyazeva I., Poyda A., Orlov V., Verkhlyutov V.M., Makarenko N., Kozlov S., Velichkovsky B., Ushakov V. Resting state dynamic functional connectivity: Network topology analysis. Biologically Inspired Cognitive Architectures. 2018. V. 23. P. 43-53. DOI: 10.1016/j.bica.2017.10.001
Portnova G.V., Tetereva A.O., Balaev V., Atanov M., Skiteva L., Ushakov V., Ivanitsky A.M., Martynova O.V. Correlation of BOLD signal with linear and nonlinear patterns of EEG in resting state EEG-informed fMRI. Frontiers in Human Neuroscience. 2018. V. 11. P. 654. DOI: 10.3389/fnhum.2017.00654
Skiteva L.I., Ushakov V.L., Verkhlyutov V.M. Analysis of Resting State according to the data of magnetoencephalography. Procedia Computer Science. 2018. V. 145. P. 520-525. DOI: 10.1016/j.procs.2018.11.116
Sysoeva O.V., Constantino J.N., Anokhin A.P. Event-related potential (ERP) correlates of face processing in verbal children with autism spectrum disorders (ASD) and their first-degree relatives: a family study. Molecular Autism. 2018. V. 9. P. 41. DOI: 10.1186/s13229-018-0220-x
Ukraintseva Y.V., Liaukovich K.M., Polishchuk A.A., Martynova O.V., Belov D.A., Simenel E.S., Meira-e-Cruz M., Nizhnik A.N. Slow-wave sleep and androgens: selective slow-wave sleep suppression affects testosterone and 17α-hydroxyprogesterone secretion. Sleep Medicine. 2018. V. 48. P. 117-126. DOI: 10.1016/j.sleep.2018.04.012
Velichkovsky B.M., Krotkova O.A., Kotov A.A., Orlov V.A., Verkhlyutov V.M., Ushakov V.L., Sharaev M.G. Consciousness in a multilevel architecture: Evidence from the right side of the brain. Consciousness and Cognition. 2018. V. 64. P. 227-239. DOI: 10.1016/j.concog.2018.06.004
Verkhlyutov V.M., Balaev V.V. The method of modeling the human EEG by calculating radial traveling waves on the folded surface of the human cerebral cortex. bioRxiv. 2018. V. -. N. 242412. P. 1-28. DOI: 10.1101/242412
Verkhlyutov V.M., Sharaev M., Balaev V., Osadtchi A., Ushakov V., Skiteva L., Velichkovsky B. Towards localization of radial traveling waves in the evoked and spontaneous MEG: A solution based on the intra-cortical propagation hypothesis. Procedia Computer Science. 2018. V. 145. P. 617-622. DOI: 10.1016/j.procs.2018.11.073
Garakh Z.V., Zaitseva Y.S., Novototsky-Vlasov V.Y., Gurovich I.Y., Shmukler A.B., Strelets V.B. The influence of instructions on the early stages of visual perception of verbal stimuli in normal and schizophrenia. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2017. V. 67. N. 1. P. 68-82. DOI: 10.7868/S0044467717010075
Garakh Z.V., Zaitseva Y.S., Oreshkina A.S., Morozova A.A., Gurovich I.Y., Shmukler A.B., Strelets V.B. Correlation of the psychological assessment of social intelligence with neurophysiological and autonomic indicators in patients with schizophrenia and mentally healthy subjects. Sotsialnaja i Klinicheskaja Psikhologija. 2017. V. 27. N. 2. P. 75-82.
Ivanitsky A.M. The descending influences from mental to physiological level as a possible base for free will mechanism. Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova. 2017. V. 67. N. 6. P. 728-729. DOI: 10.7868/S0044467717060053
Larionova E.V., Shuvalova A.A. Modern studies of the effect of tetrahydrocannabinol on higher mental functions. Psychology. Zhurnal Vysshei Shkoly Ekonomiki. 2017. V. 14. N. 1. P. 189-199. DOI: 10.17323/1813-8918.2017.1.189.199.
Lushchekina E.A., Khaerdinova O.Y., Luschekin V.S., Strelets V.B. Interhemispheric differences in spectral power and coherence of EEG rhythms in children with autism spectrum disorders. Fiziologija Cheloveka. 2017. V. 43. N. 3. P. 32-42. DOI: 10.7868/S0131164617030110
Morozova A.A., Oreshkina A.S., Garakh Z.V., Salnikova L.I., Zaitseva Y.S. Comparative analysis of scales for assessing the internal model of consciousness of another in patients with the first psychotic episode: a pilot study. Sotsialnaja i Klinicheskaja Psikhiatrija. 2017. V. 27. N. 1. P. 26-30.
Rusalova M.N. Front-occipital asymmetry inversion: EEG power and coherence with an alarming wait. Asimmetrija. 2017. V. 11. N. 2. P. 5-18.
Strelets V.B., Maslennikova A.V., Ushakov V.L., Arkhypov A.Y. fMRI for menacing stimuli in patients with acute paranoid schizophrenia. Psikhologija. 2017. V. 75. N. 3. P. 43-46.
Strelnikova G.V., Strelnikova I.V., Rusalova M.N. Features of the cognitive style and bioelectrical activity of the brain of e-sportsmen. Sovremennyje Voprosy Bimeditsiny. 2017. V. 1. N. 1. P. 92-100.
Ushakov V.L., Kartashov S.I., Orlov V.A., Zinchenko V.V., Sharaev M.G., Maslennikova A.V., Sboev A.G., Selivanova A.A., Moloschnikov I.A., Velichkovsky B.M. RICH-CLUB brain structure according to fMRI and tractography: contrasting results in healthy subjects and patients with schizophrenia. “New developments in psychological, physiological and medical neuroscience”. 2017. V. 1. P. 46-48.
Arkhipov A.Y., Maslennikova A.V., Ushakov V.L., Strelets V.B. fMRI on Affective Stimuli in Patients with Paranoid Schizophrenia. Current Trends in Biomedical Engineering & Biosciences. 2017. V. 7. N. 4. P. 555718. DOI: 10.19080/CTBEB.2017.07.555718
Arsalidou M., Sharaev M.G., Kotova T., Martynova O.V. Commentary: Selective development of anticorrelated networks in the intrinsic functional organization of the human brain. Frontiers in Human Neuroscience. 2017. V. 11. P. 13. DOI: 10.3389/fnhum.2017.00013
Gladun K.V. P274 Pleasant and unpleasant sound perception in patients with severe and moderate TBI using correlation dimension D2 analysis. Journal of Clinical Psychology. 2017. V. 128. N. 9. e266. DOI: 10.1016/j.clinph.2017.07.282
Golimbet V.E., Garakh Z.V., Korovaitseva G.I., Lezheiko T.V., Zaitseva Y.S., Gurovich I.Y., Shmukler A.B., Rodionov G.I., Strelets V.B. Association of the Brain-Derived Neurotrophic Factor and Serotonin Transporter Genes with Parameters of the Early Components of Event-Related Potentials on Passive Word Perception. Neuroscience and Behavioral Physiology. 2017. V. 47. N. 9. P. 1140-1146. DOI: 10.1007/s11055-017-0521-0
Martynova O.V., Portnova G.V., Balaev V.V., Ivanitsky A.M. Comparative Analysis of Brain Activity in Verbal and Spatial Thought in Healthy Subjects and Patients with Speech Disorders. Neuroscience and Behavioral Physiology. 2017. V. 47. N. 7. P. 767-776. DOI: 10.1007/s11055-017-0465-4
Martynova O.V., Portnova G.V., Gladun K.V. Neural correlates of brain state in chronic ischemia and stroke: Combined resting state electroencephalogram and transcranial Doppler ultrasonographic study. NeuroReport. 2017. V. 28. N. 3. P. 163-168. DOI: 10.1097/WNR.0000000000000720
Martynova O.V., Sushinskaya-Tetereva A.O., Balaev V.V., Ivanitsky A.M. Correlation between the Functional Connectivity of Brain Areas Active in the Resting State with Behavioral and Psychological Indicators. Neuroscience and Behavioral Physiology. 2017. V. 47. N. 9. P. 1128-1139. DOI: 10.1007/s11055-017-0520-1
Medvedeva T.M., Sysoeva O.V., Sysoev I.V. Modeling spike-wave discharges by a complex network of neuronal oscillators. Neural Networks. 2017. V. 98. P. 271-282. DOI: 10.1016/j.neunet.2017.12.002
Morozova A., Garakh Z.V., Bendova M., Zaytseva Y. Comparative Analysis of Theory of Mind Tests in First Episode Psychosis Patients. Psychiatr Danub.. 2017. V. 29. P. 285-288.