Laboratory of Human Higher Nervous Activity
The main areas of research
Neurophysiological basis of human cognitive functions in healthy and pathological brain
Perception
Attention
Emotions
Memory
Thinking
Consciousness (levels, content, form)
Basic research methods
Evoked potentials
EEG
Vegetative indices
fMRI (behavior and resting state)
Psychometric tests
History
The laboratory of higher nervous activity of a person was organized at the Institute in 1987. Its task was defined as studying the physiological foundations of consciousness. From 1987 to 2012, the laboratory was headed by prof. A.M. Ivanitsky, who had developed the theory of information synthesis shortly before. The theory was based on a study of the physiological processes underlying sensations. Following this theory, psychic (subjectively experienced) phenomena arise as a result of the return of excitation to areas of initial projections, comparison, and synthesis in the cortex of new information with previous extracted from memory and comes from centers of motivation.
Список сотрудников
Publication list
Papers
- Larionova E.V. Peak alpha frequency in abstinent cannabinoid users in the resting state and during cognitive task performance. Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova. 2016. V. 66. N. 6. P. 690-697. DOI: 10.7868/S0044467716060058
- Martynova O.V., Portnova G.V., Balaev V.V., Ivanitsky A.M. Comparative analysis of brain activity in verbal and spatial thinking in normal and in patients with speech impairment. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2016. V. 66. N. 3. P. 313-326.
- Martynova O.V., Portnova G.V., Orlov I.. An fMRI study of the brain activation related to intensive positive emotions during viweing erotic pictures in 49-74 Old Men. Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova. 2016. V. 66. N. 1. P. 24-35. DOI: 10.7868/S0044467715060064
- Portnova G.V., Atanov M.S., Gladun K.V., Martynova O.V. The EEG parameters of the resting states correlate with the data of MAG ultrasound and cognitive impairment in patients with chronic cerebral ischemia and stroke of various lateralization. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2016. V. 66. N. 6. P. 1-11.
- Rusalova M.N. Mental representation of emotional images: amplitude and coherent connections of alpha rhythm. Fundamental problems of neuroscience. Functional asymmetry, neuroplasticity and neurodegeneration. 2016. V. 1. N. 1. P. 15-16.
- Rusalova M.N., Mitrofanov A.A. Impulsivity and reflection in humans: asymmetry and EEG differences. Asimmetrija. 2016. V. 10. N. 2. P. 23-40. DOI: 10.18454/ASY.2016.35.2516
- Sysoeva M.V., Sitnikova E.Y., Sysoev I.V. Thalamo-cortical mechanisms of initiation, maintenance and termination of peak wave discharges in rats WAG / Rij. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2016. V. 66. N. 2. P. 103-112. DOI: 10.7868/S0044467716010123
- Balaev V., Petrushevsky A., Martynova O.V. Changes in Functional Connectivity of Default Mode Network with Auditory and Right Frontoparietal Networks in Poststroke Aphasia. Brain Connectivity. 2016. V. 6. N. 9. P. 714-723. DOI: 10.1089/brain.2016.0419
- Ivanitsky A.M. Determinism and Free Choice in the Operation of the Brain. Neuroscience and Behavioral Physiology. 2016. V. 46. N. 9. P. 1-8. DOI: 10.1007/s11055-016-0355-1
- Portnova G.V. Moderate and severe TBI patients distinguish emotional stimuli unlikely to healthy adults: EEG and behavioural research. Brain Injury. 2016. V. 30. N. 5. P. 508.
- Portnova G.V., Atanov M.S. Age-Dependent Changes of the EEG Data: Comparative Study of Correlation Dimension D2, Spectral Analysis, Peak Alpha Frequency and Stability of Rhythms. International Journal of Innovative Research in Computer Science & Technology. 2016. V. 4. N. 2. P. 2347-5552.
- Portnova G.V., Gladun K.V. Tactile Stimulation in Acute Tbi Comas. a Comparative Analysis of Healthy Adults and Children. International Journal of Scientific Research. 2016. V. 5. N. 1. P. 1. DOI: 10.15373/22778179
- Rebreikina A.B., Larionova E.V., Varlamov A.A. Evoked Changes in the Rhythmic Activity of the Brain during Processing of Visually Presented Target, Nontarget, and Unknown Words. Neuroscience and Behavioral Physiology. 2016. V. 46. N. 5. P. 494-503. DOI: 10.1007/s11055-016-0265-2
- Strelets V.B., Arkhipov A.Y., Garakh Z.V. Latencies of the Sensory and Cognitive Components of Event-Related Potentials on Perception of Verbal Stimuli in Health and Schizophrenia. Neuroscience and Behavioral Physiology. 2016. V. 46. N. 9. P. 1024-1030. DOI: 10.1007/s11055-016-0348-0
- Ushakov V.L., Sharaev M.G., Kartashov S.I., Zavyalova V.V., Verkhlyutov V.M., Velichkovsky B.M. Dynamic causal modeling of hippocampal links within the human default mode network: Lateralization and computational stability of effective connections. Frontiers in Human Neuroscience. 2016. V. 10. N. OCT2016. P. 528. DOI: 10.3389/fnhum.2016.00528
- Verkhlyutov V.M., Sokolov P.A., Ushakov V.L., Velichkovskii B.M. Macroscopic Functional Networks in the Human Brain on Viewing and Recalling Short Video Clips. Neuroscience and Behavioral Physiology. 2016. V. 46. N. 8. P. 934-941. DOI: 10.1007/s11055-016-0334-6
- Verkhlyutov V.M., Sokolov P.A., Ushakov V.L., Velichkovsky B.M. Macroscopic Functional Networks of the Human Brain when Viewing and Recalling Short Videos. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2015. V. 65. N. 3. P. 333-343.
- Garakh Z.V., Zaitseva Y.S., Gurovich I.Y., Shmukler A.B., Strelets V.B. Neurophysiological and autonomic indicators of motor imagination in patients with schizophrenia and schizoaffective disorder. Sotsialnaja i Klinicheskaja Psikhiatrija. 2015. V. 25. N. 3. P. 25-31.
- Larionova E.V., Garakh Z.V., Novototsky-Vlasov V.Y. P100 and N170 components of ERPs in abstinent cannabinoid users during the modified stroop task. Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova. 2015. V. 65. N. 4. P. 420-428. DOI: 10.7868/S0044467715040073
- Lushchekina E.A., Khaerdinov O.Y., Novotocky-Vlasov V.Y., Lushyokin V.S., Strelets V.B. EEG Synchronisation in Autistic Children. Analysis of Coherency. Zhurnal Vysshei Nervnoi Deiatelnosti im. I.P.Pavlova. 2015. V. 65. N. 1. P. 72-81. DOI: 10.7868/S0044467715010074
- Rebreikina A.B., Larionova E.V., Varlamov A.A. Caused changes in the rhythmic activity of the brain during the processing of visually presented target, non-target and unfamiliar words. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2015. V. 65. N. 1. P. 92-104. DOI: 10.7868/S004446771501013X
- Rusalova M.N. The amplitude of the alpha rhythm as an indicator of the stability of mental reproduction of emotional images from memory. Asimmetrija. 2015. V. 9. N. 4. P. 4-17. DOI: 10.18454/ASY.2015.34.732
- DosSantos G., Schroeder A.J., Goodman J.L., Strelets V.B., Crosby M.A., Thurmond J., Emmert D.B., Gelbart W.M., Brown N.H., Kaufman T., Werner-Washburne M., Cripps R., Broll K., Gramates L.S., Falls K., Matthews B.B., Russo S., Zhou P., Zytkovicz M., Adryan B., Attrill H., Costa M., Marygold S., McQuilton P., Millburn G., Ponting L., Stefancsik R., Tweedie S., Grumbling G. FlyBase: Introduction of the Drosophila melanogaster Release 6 reference genome assembly and large-scale migration of genome annotations. Nucleic Acids Research. 2015. V. 43. N. D1. D690-D697. DOI: 10.1093/nar/gku1099
- Garakh Z.V., Zaytseva Y., Kapranova A., Fiala O., Horacek J., Shmukler A., Gurovich I.Y., Strelets V.B. EEG correlates of a mental arithmetic task in patients with first episode schizophrenia and schizoaffective disorder. Clinical Neurophysiology. 2015. V. 126. N. 11. P. 2090-2098. DOI: 10.1016/j.clinph.2014.12.031
- Ivanitskii A.M., Portnova G.V., Martynova O.V., Maiorova L.A., Fedina O.N., Petrushevskii A.G. Brain Mapping in Verbal and Spatial Thinking. Neuroscience and Behavioral Physiology. 2015. V. 45. N. 2. P. 146-153. DOI: 10.1007/s11055-015-0052-5
- Zaytseva Y., Bendova M., Garakh Z.V., Tintera J., Rydlo J., Spaniel F., Horacek J. In search of neural mechanisms of mirror neuron dysfunction in schizophrenia: resting state functional connectivity approach. Psychiatr. Danub.. 2015. V. 27. P. 269-272.
- Garakh Z.V., Zaitseva Y.S., Novototsky-Vlasov V.Y., Khaerdinova O.Y., Gurovich I.Y., Schmukler A.B., Strelets V.B. EEG mu rhythm suppression in the presentation of movement in patients with schizophrenia. Social and Clinical Psychiatry. 2014. V. 24. N. 3. P. 5-11.
- Lushchekina E.A., Strelets V.B. Features of synchronization of EEG rhythms in the background and during the counting activity in children with autism spectrum disorders. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2014. V. 64. N. 6. P. 585-599. DOI: 10.7868/S0044467715010074
- Mayorova L.A., Martynova O.V., Balaban P.M., Ivanitsky A.M., Schklovskii V.N. Mismatch negativity and its hemodynamic equivalent (based on fMRI) in research of speech perception in healthy and in speech disorders. Uspehi Fiziologicheskikh Nauk. 2014. V. 45. N. 1. P. 27-43.
- Portnova G.V., Martynova O.V., Ivanitsky G.A. Age-related differences in auditory evoked potentials in the perception of sequential and spatial components of audio information. Fizioligija Cheloveka. 2014. V. 40. N. 1. P. 26-35.
- Rusalova M.N. Asymmetry of the alpha rhythm in the mental reproduction of emotional images. Asimmetrija. 2014. V. 8. N. 2. P. 5-20.
- Rusalova M.N. Asymmetry of coherent relationships in the mental reproduction of emotional images. Asimmetrija. 2014. V. 8. N. 4. P. 24-41.
- Simonova N.A., Garakh Z.V., Zaitseva Y.S., Schmukler A.B. Neurophysiological mechanisms of visual impairment in schizophrenia. Sotsialnaja i Klinicheskaja Psikhiatrija. 2014. V. 24. N. 1. P. 81-89.
- Balaev V., Mayrova L., Petrushevsky A., Martynova O.V. Functional connectivity in chronic stroke compared with normal aging changes. Brain Connectivity. 2014. V. 4. N. 9. A95.
- Garakh Z.V., Yukhnenko D.V., Strelets V.B. Sensory analysis of the words with different occurrence frequency in the norm and in patients with schizophrenia and schizophrenic spectrum disorders. Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova. 2014. V. 64. N. 4. P. 376-387. DOI: 10.7868/S0044467714040066
- Portnova G.V., Gladun K.V., Ivanitskii A. The EEG Analysis of Auditory Emotional Stimuli Perception in TBI Patients with Different SCG Score. Open Journal of Modern Neurosurgery. 2014. V. 4. N. 2. P. 81-96. DOI: 10.4236/ojmn.2014.42017.
- Portnova G.V., Martynova O.V. Auditory ERP Differences in the Perception of Anticipated Speech Sequences in 5 - 6 Years Old Children and Adults. Journal of Behavioral and Brain Science. 2014. V. 4. P. 412-422. DOI: 10.4236/jbbs.2014.49040
- Rebreikina A.B., Strelets V.B. Characteristics of the early stages of processing of target and nontarget known and unknown verbal stimuli. Neuroscience and Behavioral Physiology. 2014. V. 44. N. 1. P. 24-30. DOI: 10.1007/s11055-013-9867-0
- Sysoeva O.V., Sitnikova E.Y., Sysoev I.V., Bezruchko B.P., van Luijtelaar G. Application of adaptive nonlinear Granger causality: disclosing network changes before and after absence seizure onset in a genetic rat model. Journal Of Neuroscience Methods. 2014. V. 226. P. 33-41. DOI: 10.1016/j.jneumeth.2014.01.028
- Verkhlyutov V.M., MarIna I.V., Strelets V.B. Event-related spectral EEG power on presentation of pseudowords and words of the "animate" and "inanimate" categories. Neuroscience and Behavioral Physiology. 2014. V. 44. N. 1. P. 16-23. DOI: 10.1007/s11055-013-9866-1
- Verkhlyutov V.M., Ushakov V.L., Sokolov P.A., Velichkovsky B.M. Large-scale network analysis of imagination reveals extended but limited top-down components in human visual cognition. Psychology in Russia: State of the Art. 2014. V. 7. N. 4. P. 4-19. DOI: 10.11621/pir.2014.0401
- Varlamov A.A., Strelets V.B. EEG coherence analysis in depressive disorders and its possible use in clinical practice: a literature review. Zhurnal vyssheĭ nervnoĭ deiatelnosti imeni I P Pavlova. 2013. V. 63. N. 6. P. 613-624. DOI: 10.7868/S004446771306018X
- Ivanitsky A.M., Portnova G.V., Martynova O.V., Mayorova L.A., Fedina O.N., Petrushevsky A.G. Brain mapping in verbal and spatial thinking. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2013. V. 63. N. 6. P. 677-686.
- Larionova E.V. Cognitive disorders and some particularly of brain electrical activity in the use of cannabinoids. Zhurnal vyssheĭ nervnoĭ deiatelnosti imeni I P Pavlova. 2013. V. 63. N. 6. P. 643-655. DOI: 10.7868/S0044467713060105
- Larionova E.V. Magnetic resonance spectroscopy in the study of mnestic activity. Vestnik Moskovskogo Universiteta. Serija 14. Psikhologija. 2013. V. 3. P. 59-72.
- Lushchekina E.A., Podreznaya E.D., Luschekin V.S., Novototsky-Vlasov V.Y., Strelets V.B. Comparative study of theta and gamma rhythms of the EEG in normal and early childhood autism. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2013. V. 63. N. 4. P. 451-459. DOI: 10.7868/S0044467713040072
- Mayorova L.A., Martynova O.V., Fedina O.N., Petrushevsky A.G. FMRI study of speech impairment in patients with post-stroke sensory aphasia. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2013. V. 63. N. 3. P. 328-337.
- Maslennikova A.V., Varlamov A.A., Strelets V.B. Features of evoked changes in spectral power and evoked EEG potentials in the perception of musical harmony among musicians and non-musicians. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2013. V. 63. N. 5. P. 571.
- Petrushevsky A.G., Mayorova L.A., Martynova O.V., Fedina O.N. Factors affecting the characteristics of the BOLD response in patients after stroke. Vestnik RNCRR. 2013. V. 13. ??.
- Petrushevsky A.G., Fedina O.N., Martynova O.V., Mayorova L.A. Correlation of fMRI data with clinical indicators of speech impairment in patients with sensory aphasia. Nevskij Radiologicheskij Forum. 2013. V. 1. P. 256.